Acute liver failure: Current trends
نویسندگان
چکیده
منابع مشابه
Acute liver failure: current management and future prospects.
Although the development of hepatic encephalopathy (HE) and the associated increase in intracranial pressure (ICP) in patients with acute liver injury is the key event that defines their prognosis [1–5], ALF is associated with dysfunction of multiple organ systems. The circulatory disturbance in ALF is an early manifestation that tends to worsen during the course of the illness and is character...
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Acute liver failure in children is associated with a high mortality. Most cases in our setup are due to water borne hepatotropic viruses HAV and HEV. The clinician must be aware of the earliest and the subtle signs of acute liver failure to identify cases early enough and institute supportive therapy. Focus of therapy has to be on prevention, early recognition and appropriate management of comp...
متن کاملAcute Liver Failure
Acute liver failure (ALF) (sometimes referred to as fulminant hepatic failure) is a clinical syndrome from a variety of causes resulting from rapid loss in hepatocyte function, typically associated with coagulopathy and encephalopathy in a patient without preexisting liver disease or cirrhosis. Cerebral edema is a cardinal feature and may produce uncal herniation, yielding brain stem compressio...
متن کاملAcute Liver Failure
The development of encephalopathy in patients with acute liver injury defines the occurrence of liver failure. The encephalopathy of acute liver failure is characterized by brain edema which manifests clinically as increased intracranial pressure. Despite the best available medical therapies a significant proportion of patients with acute liver failure die due to brain herniation. The present r...
متن کاملAcute liver failure.
Acute liver failure is a rare but often catastrophic illness affecting the liver and multiple organ systems. Patients with acute liver failure require a multidisciplinary approach for adequate management. With improved critical care and the availability of liver transplantation, survival has significantly improved. Hepatic encephalopathy, cerebral edema and infections are the most common compli...
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ژورنال
عنوان ژورنال: Journal of Hepatology
سال: 2013
ISSN: 0168-8278
DOI: 10.1016/j.jhep.2013.04.001